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Good news about boosters

Here's the latest news from the global pandemic.

The good news about boosters

You have to learn something and forget it six times before it's permanently in your head, my French teacher told me. Immunity works in a similar way. The more our immune system sees a pathogen, the better and faster it is at recalling how to fight it. 

Waning antibody levels in some highly vaccinated populations such as Israel have prompted calls to offer Covid booster shots to blunt fresh waves of hospitalizations in the face of the delta variant

So far, third doses seem to be working

Photographer: Allen J. Schaben/Los Angeles Times

Photographer: Allen J. Schaben/Los Angeles Times

In fully vaccinated, healthy adults, booster shots from Moderna as well as Pfizer and its partner BioNTech cause antibodies to rebound to peak levels, if not well beyond, says Shane Crotty, a virologist and professor at the La Jolla Institute for Immunology's Center for Infectious Disease and Vaccine Research in California. 

Those antibodies are also likely to be more durable and adept at fighting a wider range of SARS-CoV-2 strains. All that fits with what we know about the mechanics of immune memory generation"that it's frequently taken three exposures to get that," Crotty says.

The response to boosters is the good news. The bad news is that large swaths of people in low- and middle-income nations are yet to get a sniff of any vaccine. Dozens of countries have administered at least one dose per person. Yet, as of Aug. 19, West Africa has delivered 2.4 doses per 100 people. In East and Southern Africa, the figure stands at 4.8 doses per 100 people.

Booster doses in the context of such inequity is like handing out extra life vests to people who already have them, while we're leaving other people to drown, says Mike Ryan, executive director of the World Health Organization's health emergencies program.—Jason Gale

Masking up 

Ron DeSantis and Florida's Back-to-School Revolt 

Florida's GOP governor, his eye on the 2024 presidential race, is standing firm against mask mandates, even with Covid rampant in the state. Get the full story here.

Ron DeSantis, governor of Florida.

Photographer: Eva Marie Uzcategui/Bloomberg

 

What you should read

Impossible Is Now Commonplace on Wall Street
One lesson from market's relentless climb: sometimes rules don't matter.
Australia's Vaccine Rate Rises, So Does Delta 
Lockdown fails to flatten infection curve as NSW records fresh record.
Study Backs Boosters for Weak Immune Systems
40% of immune compromised responded weakly to standard courses.
Vaccine Efficacy Diminished as Delta Arose
CDC advisers to consider data on boosters next week in meeting.
Activists: Use Federal Aid for Relief, Not Debt
Officials urged to make sure local governments get relief to most in need.

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