| A new study comparing the risk of blood clots from vaccines with that of Covid-19 has helped put one of the most often-cited reasons for avoiding vaccination into context. According to the large U.K. study, Covid-19 causes thousands more clots compared with shots from AstraZeneca or the partnership of Pfizer and BioNTech. For every 10 million people who receive the first dose of Astra, only 66 people are likely to suffer a rare clotting syndrome, on top of the normal cases expected in that population, the study reported. But in the same number of people who test positive for Covid-19, 12,614 potentially life-threatening clots would be expected. The findings support the government's message that the benefits of Covid-19 vaccines outweigh the risk of serious adverse events seen in a relatively small number of the population. What's more, ongoing research into the side effects has helped policymakers determine who should receive particular vaccines. Restricting the use of Astra's shot to those over age 40 has virtually ended reports of rare clotting episodes, which had been seen most frequently in younger people.  AstraZeneca's vaccine Photographer: SAEED KHAN/AFP The findings in particular support governments' efforts to encourage the use of Astra's vaccine. Vaccine hesitancy has derailed attempts by public health officials to get populations immunized, as the number of infections globally rise rapidly, driven by the highly contagious delta variant. In some cases, doses of vaccine have expired unused because of concerns about side effects, many of them unfounded or tied to misinformation. The study found a higher chance of the virus contributing to a stroke than the first dose of the shot developed by Pfizer with partner BioNTech. The vaccine increases the risk of a low platelet count, but contracting Covid-19 makes the risk of the side effects nine times more likely. The researchers weren't able to establish whether the identified cases of blood clots were definitively caused by the vaccines, although some have found a potential link. But for people who have used blood clot risk as a reason to avoid the vaccine, the threat of Covid should serve as justification of getting the shot.
Safety concerns surrounding the vaccines should not be ignored, the study authors concluded, but the risks of life-threatening clotting should be viewed in the appropriate light.—Grace Gitau | 
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