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J&J's second act

Here's the latest news from the global pandemic.

Johnson & Johnson's second act

For Americans wary of the Johnson & Johnson vaccine as it returns to use after a probe of a potentially deadly side effect, health experts have a message: The system worked.

U.S. health agencies lifted a hold on the vaccine last Friday after a review of rare blood clots seen in 15 people out 8 million who received it. The CDC determined the J&J vaccine could prevent some 1,435 Covid deaths and 2,236 hospitalizations over the next six months, compared with a projected 26 possible clot cases. Put another way, the benefits of the shot far outweighed the minuscule risk of clots potentially linked to it.

Those overseeing the U.S. vaccination effort hope the scientific scrutiny will put people at ease. But the pause may have made it harder to persuade those who are vaccine-hesitant to roll up their sleeves. To reach the uncertain, a more tailored message is needed.

"There's not a one-size-fits-all approach in a country of 350 million," says Ezekiel Emanuel, a medical ethicist at the University of Pennsylvania.

Syringes with prepared doses of the Johnson & Johnson Covid-19 vaccine.

Photographer: David Paul Morris/Bloomberg

There are hints that the messaging is already working—states are seeing high interest in the shot. This past Saturday, hours after the halt lifted, people at the Indianapolis Motor Speedway were offered a choice between the J&J and Pfizer vaccines. By the end of the day, the site had given 2,515 J&J shots, or 83% of the roughly 3,000 total doses administered.

"I'm hoping as we get through this weekend and we start seeing no further concerns, people realize it's still a very safe vaccine," said Mary Kay Foster, co-lead of the Indiana University Health mass-vaccination campaign. She noted women at the site remained wary, often opting for Pfizer's shot instead.

Health officials suggest the risk to women from the vaccine is very low. All 15 cases of the clotting condition were seen in women, and 13 were under age 50—amounting to 7 cases per million doses for women in that age group. The benefits and risks should be "clearly discussed and weighed in a way that is not perpetuating anxiety," says Kathryn Schubert, president of the Society for Women's Health Research.

U.S. officials should also signal confidence to the international community, says Emanuel, who advised President Joe Biden's Covid transition team. The J&J vaccine is cheap, easily stored and administered in a single dose. Those qualities make it a critical tool for battling outbreaks in countries that lack sophisticated health infrastructure.

"We should tout to the international community how transparent we were, that all the data was on the table," he says. "That's our greatest strength as a country."—Riley Ray Griffin and Angelica LaVito

Track the vaccines

More than 1.8 Billion Shots Given

Enough doses have now been administered to fully vaccinate about 7% of the global population—but the distribution has been lopsided. Countries with the highest incomes are getting vaccinated 25 times faster than those with the lowest. We've updated our vaccine tracker to allow you to explore vaccine rates vs Covid-19 cases in a number of countries. See the latest here.

Syringes loaded with doses of a Covid-19 vaccine.

Photographer: KAMIL KRZACZYNSKI/AFP

 

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The Car Is Making a Big Pandemic Comeback 
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U.K. Deploys Ravers to Test Relaxing of Rules
The 6,000 clubbers are part of trials into reopening mass events safely. 

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