| The hazy picture surrounding an experimental vaccine from China became a little clearer this week. Developed by Sinovac Biotech Ltd., the two-dose vaccine was found to be 78% effective against Covid-19 in late-stage trials in Brazil. It's the most definitive result so far on the shot's efficacy after previous data sparked confusion and doubt. The results offered some promising news at a time when infections and deaths are surging around the globe. The protection rate, confirmed by Sao Paulo state officials, was derived from Sinovac's most advanced final-stage trials involving about 13,000 participants. The rate is shy of the roughly 95% effectiveness seen in mRNA vaccines developed by Pfizer Inc. and Moderna Inc. The vaccine was 78% effective in preventing mild cases of Covid-19 and 100% effective against severe and moderate infections, said Dimas Covas, director of the Butantan Institute, which partnered with Sinovac to produce the shot locally. The trial saw about 220 participants infected -- 160 in the placebo group and almost 60 among those who received the vaccine, Covas said. Officials declined to provide a more detailed breakdown of the study, including information about age groups and side effects of the shot, and didn't specify when the full documentation will be published. It also wasn't clear how the Brazilian researchers calculated the efficacy rate. The institute declined to elaborate further, saying it had no information beyond what was released at the press conference.  A box of Sinovac Biotech coronavirus trial vaccine is displayed at Palacio Bandeirantes in Sao Paulo Photographer: Rodrigo Paiva/Getty Images South America Conflicting and incomplete information from Sinovac's trials last month created confusion over exactly how effective the shot is. Researchers in Brazil delayed releasing complete data on the vaccine in late December, saying only that it was found to be more than 50% effective. Sao Paulo state Health Secretary Jean Gorinchteyn later said the vaccine didn't reach 90% efficacy. Further confusing matters, Turkey said its trial showed an estimated efficacy rate of 91.25%, though that was based on only 29 cases. The release of more definitive data on the vaccine's efficacy was delayed because the Beijing-based developer needed to reconcile results from different trials using varying protocols, according to a person familiar with the matter. While Sinovac's latest disclosure now provides a better picture of its vaccine's effectiveness and should shore up confidence in countries where it has inked supply deals like Indonesia and Brazil, the Chinese developers' lack of timely and clear disclosures has contributed to a lack of trust. That's one thing public health officials need when they are trying to persuade people to roll up their sleeves.--Andre Romani Pinto | 
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