Miraculous medical breakthroughs are coming at a breakneck pace—even as diseases once thought vanquished return to haunt us. At this past week's American Society of Clinical Oncology meeting, a new drug from AstraZeneca was shown to slow the spread of a rare pancreatic cancer. Early results from a study of an Amgen drug raised new hopes for lung-cancer patients. Each of those therapies hinges upon cutting-edge genetic research that would have seemed like fantasy a generation ago. Leaps in genetic science are also yielding one-shot cures for diseases that once were beyond the grasp of medicine. Gene therapy has appeared to successfully treat incurable patients like Omarion Jordan, whose harrowing "bubble boy" disease has been reversed. As science races ahead, these new medical wonders will likely cost patients millions. Meanwhile, the rewards of a great breakthrough of another era are being eroded. U.S. public-health officials reported that measles cases in the first five months of 2019 topped the total cases per year for the past 25 years. A simple, inexpensive inoculation that spared millions of children from sickness for decades has fallen under uninformed suspicion, with potentially ruinous consequences for society. The development of childhood vaccines was one of the great scientific achievements of the 20th century, standing alongside the moon landing and the theory of relativity as monuments to human intelligence. For all our awe at the miracles of today, the ones we've come to take for granted are under attack.—Tim Annett Here's what else we're watchingPain pact. Insys Therapeutics has agreed to pay $225 million to settle U.S. opioid-sales investigations. The future of the Arizona drugmaker is uncertain as former top executives await sentencing for fraud convictions. Health hack. Congress is curious about a hack of a medical-bill collector that has exposed the personal information of roughly 20 million people so far. Health-care data is a tantalizing target for identity thieves.
Twin twist. A new study suggests that the genetic mutation a Chinese researcher claimed he used to create HIV-resistant twins may be linked to a shorter lifespan. Bio boom. Third Rock Ventures raised $770 million, amassing the largest war chest it has ever had to invest in nascent life-sciences firms. Despite rocky stock markets, investors still seem hungry for risky biotech bets. Listen up. Season two of our podcast is all about what happens when we hand over our health data to companies and governments. Download it here on Apple devices, and here on Android.  Got this newsletter forwarded to you? Sign up to get it every Thursday by clicking here.
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